6XSK
Cryo-EM Structure of Vaccine-Elicited Rhesus Antibody 789-203-3C12 in Complex with Stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | L, J, K | 789-203-3C12 Fab Light Chain | polymer | 214 | 23209.7 | 3 | Macaca mulatta | ||
2 | H, G, I | 789-203-3C12 Fab Heavy Chain | polymer | 455 | 49298.6 | 3 | Macaca mulatta | ||
3 | A, C, E | Hemagglutinin HA1 chain | polymer | 343 | 38269.2 | 3 | UniProt (A7Y8I1) Pfam (PF00509) In PDB | Influenza A virus (A/Solomon Islands/3/2006(H1N1)) | |
4 | B, D, F | Hemagglutinin HA2 chain | polymer | 222 | 25264.1 | 3 | UniProt (A7Y8I1) Pfam (PF00509) In PDB | Influenza A virus (A/Solomon Islands/3/2006(H1N1)) | |
5 | M, Q, T | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
6 | N, O, P, R, S... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 6 | In PDB GlyTouCan (G42666HT) | |||
7 | C, D, E, F, A... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 15 | Chemie (NAG) |
Sequence modifications
A, C, E: -6 - 329 (UniProt: A7Y8I1)
B, D, F: 1 - 176 (UniProt: A7Y8I1)
PDB | External Database | Details |
---|---|---|
Cys 30 | Leu 37 | conflict |
PDB | External Database | Details |
---|---|---|
Cys 47 | Gly 390 | conflict |
Ser 177 | - | expression tag |
Gly 178 | - | expression tag |
Arg 179 | - | expression tag |
Leu 180 | - | expression tag |
Val 181 | - | expression tag |
Pro 182 | - | expression tag |
Arg 183 | - | expression tag |
Gly 184 | - | expression tag |
Ser 185 | - | expression tag |
Pro 186 | - | expression tag |
Gly 187 | - | expression tag |
Ser 188 | - | expression tag |
Gly 189 | - | expression tag |
Tyr 190 | - | expression tag |
Ile 191 | - | expression tag |
Pro 192 | - | expression tag |
Glu 193 | - | expression tag |
Ala 194 | - | expression tag |
Pro 195 | - | expression tag |
Arg 196 | - | expression tag |
Asp 197 | - | expression tag |
Gly 198 | - | expression tag |
Gln 199 | - | expression tag |
Ala 200 | - | expression tag |
Tyr 201 | - | expression tag |
Val 202 | - | expression tag |
Arg 203 | - | expression tag |
Lys 204 | - | expression tag |
Asp 205 | - | expression tag |
Gly 206 | - | expression tag |
Glu 207 | - | expression tag |
Trp 208 | - | expression tag |
Val 209 | - | expression tag |
Leu 210 | - | expression tag |
Leu 211 | - | expression tag |
Ser 212 | - | expression tag |
Thr 213 | - | expression tag |
Phe 214 | - | expression tag |
Leu 215 | - | expression tag |
Gly 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
His 219 | - | expression tag |
His 220 | - | expression tag |
His 221 | - | expression tag |
His 222 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 408124.7 | |
Branched | Number of molecules | 9 |
Total formula weight | 4306.0 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 3318.1 | |
All* | Total formula weight | 415748.9 |