6XQY

Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae at pH 9.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable peptidoglycan D,D-transpeptidase PenA	polymer	327	35284.3	2	UniProt (P08149) Pfam (PF00905)	Neisseria gonorrhoeae	Penicillin-binding protein 2,PBP-2
2	C (B)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	D, E (A, B)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A, B: 237 - 282 (UniProt: P08149)

PDB	External Database	Details
Asp 235	-	expression tag
Met 236	-	expression tag

A, B: 298 - 574 (UniProt: P08149)

PDB	External Database	Details
Gly 296	-	linker
Gly 297	-	linker
Ala 310	Ser 310	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70568.6
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	70604.0

*Water molecules are not included.