6XQV
Crystal structure of the catalytic domain of PBP2 S310A from Neisseria gonorrhoeae in a pre-acylation complex with ceftriaxone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Probable peptidoglycan D,D-transpeptidase PenA | polymer | 327 | 35284.3 | 2 | UniProt (P08149) Pfam (PF00905) | Neisseria gonorrhoeae | Penicillin-binding protein 2,PBP-2 |
| 2 | C, G, H (A, B) | Ceftriaxone | non-polymer | 554.6 | 3 | Chemie (9F2) | |||
| 3 | D, E, I (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A, B: 237 - 295 (UniProt: P08149)
A, B: 298 - 574 (UniProt: P08149)
| PDB | External Database | Details |
|---|---|---|
| Asp 235 | - | expression tag |
| Met 236 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 296 | - | linker |
| Gly 297 | - | linker |
| Ala 310 | Ser 310 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70568.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1987.4 | |
| All* | Total formula weight | 72556.0 |
