6XQP
Structure of human D462-E4 TCR in complex with human MR1-5-OP-RU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Major histocompatibility complex class I-related gene protein | polymer | 271 | 31711.7 | 2 | UniProt (Q95460) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I-related gene protein,Class I histocompatibility antigen-like protein |
| 2 | B, D (B, D) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | E, G (E, G) | TRAV12-2 alpha chain | polymer | 205 | 22740.1 | 2 | Homo sapiens (Human) | ||
| 4 | F, H (F, H) | TRBV29-1 | polymer | 248 | 27694.8 | 2 | Homo sapiens (Human) | ||
| 5 | I, K (A, C) | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol | non-polymer | 316.3 | 2 | Chemie (2LJ) | |||
| 6 | J, L, M, N, P... (A, C, F, H) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 7 | O, T (E, G) | BROMIDE ION | non-polymer | 79.9 | 2 | Chemie (BR) | |||
| 8 | Q (F) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 9 | R, S, W, X (F, H) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 10 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 270 (UniProt: Q95460)
B, D: 2 - 100 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 261 | Cys 283 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 188051.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1601.9 | |
| All* | Total formula weight | 189653.8 |
