6XPD
Cryo-EM structure of human ZnT8 double mutant - D110N and D224N, determined in outward-facing conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | B, A | Zinc transporter 8 | polymer | 320 | 35086.2 | 2 | UniProt (Q8IWU4) Pfam (PF01545) In PDB | Homo sapiens (Human) | ZnT-8,Solute carrier family 30 member 8 |
| 2 | B, A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
B, A: 50 - 369 (UniProt: Q8IWU4)
| PDB | External Database | Details |
|---|---|---|
| Asn 110 | Asp 61 | engineered mutation |
| Asn 224 | Asp 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70172.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 70434.0 |
