6XP5
Head-Middle module of Mediator
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Mediator of RNA polymerase II transcription subunit 21 | polymer | 135 | 15718.7 | 1 | UniProt (G0S8E0) Pfam (PF11221) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | |
| 2 | B (D) | Mediator of RNA polymerase II transcription subunit 4 | polymer | 341 | 37924.7 | 1 | UniProt (G0S7Z4) Pfam (PF10018) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 4 |
| 3 | C (F) | Mediator of RNA polymerase II transcription subunit 6 | polymer | 337 | 36470.8 | 1 | UniProt (G0SGT8) Pfam (PF04934) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 6 |
| 4 | D (G) | Mediator of RNA polymerase II transcription subunit 7 | polymer | 246 | 27738.2 | 1 | UniProt (G0SEM4) Pfam (PF05983) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | |
| 5 | E (I) | Mediator of RNA polymerase II transcription subunit 9 | polymer | 179 | 18325.6 | 1 | UniProt (G0S292) Pfam (PF07544) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 9 |
| 6 | F (N) | Mediator of RNA polymerase II transcription subunit 14 | polymer | 1171 | 133450.4 | 1 | UniProt (G0SCL5) Pfam (PF08638) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 14 |
| 7 | G (Q) | Mediator of RNA polymerase II transcription subunit 17 | polymer | 634 | 69616.9 | 1 | UniProt (G0S1R5) Pfam (PF10156) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 17 |
| 8 | H (Z) | Mediator of RNA polymerase II transcription subunit 31 | polymer | 124 | 14486.6 | 1 | UniProt (G0S1W4) Pfam (PF05669) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | |
| 9 | I (H) | Mediator of RNA polymerase II transcription subunit 8 | polymer | 290 | 32098.5 | 1 | UniProt (G0SCZ3) Pfam (PF10232) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 8 |
| 10 | J (K) | Mediator of RNA polymerase II transcription subunit 11 | polymer | 238 | 25504.3 | 1 | UniProt (G0SH09) Pfam (PF10280) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 11 |
| 11 | K (R) | Mediator of RNA polymerase II transcription subunit 18 | polymer | 340 | 38725.8 | 1 | UniProt (G0RYQ4) Pfam (PF09637) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 18 |
| 12 | L (V) | Med22 | polymer | 169 | 18341.6 | 1 | UniProt (G0S3J8) Pfam (PF06179) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | |
| 13 | M (a) | Mediator of RNA polymerase II transcription subunit 1 | polymer | 736 | 81633.3 | 1 | UniProt (G0SEC7) Pfam (PF10744) | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | Mediator complex subunit 1 |
| 14 | N (b) | Unknown peptide | polymer | 21 | 1805.2 | 1 | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) | ||
| 15 | O (c) | HEAT | polymer | 200 | 17039.0 | 1 | Chaetomium thermophilum |
Sequence modifications
F: 1 - 314 (UniProt: G0SGT8)
N: 1 - 1181 (UniProt: G0SCL5)
V: 1 - 169 (UniProt: G0S3J8)
a: 1 - 736 (UniProt: G0SEC7)
| PDB | External Database | Details |
|---|---|---|
| Ala 136 | - | insertion |
| Phe 206 | Thr 228 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 741 | - | insertion |
| Ala 742 | - | insertion |
| Ala 743 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Ala 78 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Leu 240 | Asn 240 | conflict |
| Glu 318 | Asp 318 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 568879.4 | |
| All* | Total formula weight | 568879.4 |
