6XOQ

DCN1 covalently bound to inhibitor 4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Lysozyme, DCN1-like protein 1 chimera	polymer	386	44347.4	1	UniProt (D9IEF7) UniProt (Q96GG9) Pfam (PF00959) Pfam (PF03556)	Enterobacteria phage T4	Endolysin,Lysis protein,Muramidase,DCUN1 domain-containing protein 1,Defective in cullin neddylation protein 1-like protein 1,Squamous cell carcinoma-related oncogene
2	B (A)	(2E)-N-[(2S)-2-cyclohexyl-2-({N-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alanyl}amino)ethyl]-4-(morpholin-4-yl)but-2-enamide	non-polymer		597.8	1	Chemie (H9S)
3	C (A)	water	water		18.0	261	Chemie (HOH)

Sequence modifications

A: 1 - 164 (UniProt: D9IEF7)

PDB	External Database	Details
Met -23	-	initiating methionine
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag
Thr 54	Cys 54	engineered mutation
Ala 97	Cys 97	engineered mutation
Ala 127	Asp 127	engineered mutation
Thr 146	Ala 146	engineered mutation
Ala 154	Arg 154	engineered mutation

A: 1062 - 1259 (UniProt: Q96GG9)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44347.4
Non-Polymers*	Number of molecules	1
	Total formula weight	597.8
All*	Total formula weight	44945.2

*Water molecules are not included.