6XNZ
Structure of RAG1 (R848M/E649V)-RAG2-DNA Target Capture Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | V(D)J recombination-activating protein 1 | polymer | 750 | 85750.8 | 2 | UniProt (P15919) Pfam (PF00097) Pfam (PF10426) Pfam (PF12940) Pfam (PF26024) Pfam (PF26025) Pfam (PF26100) Pfam (PF26101) Pfam (PF26104) Pfam (PF26105) | Mus musculus (Mouse) | RAG-1 |
| 2 | B, D (B, D) | V(D)J recombination-activating protein 2 | polymer | 363 | 40417.0 | 2 | UniProt (P21784) Pfam (PF03089) | Mus musculus (Mouse) | RAG-2 |
| 3 | E (I) | Target DNA top strand (37-mer) | polymer | 37 | 11368.3 | 1 | Mus musculus | ||
| 4 | F (J) | Target DNA bottom strand (37-mer) | polymer | 37 | 11408.3 | 1 | Mus musculus | ||
| 5 | G (x) | 12RSS integration strand (34-mer) | polymer | 34 | 10456.7 | 1 | Mus musculus | ||
| 6 | H (M) | 12RSS non-integration strand (34-mer) | polymer | 34 | 10461.8 | 1 | Mus musculus | ||
| 7 | I (y) | 23RSS integration strand (45-mer) | polymer | 45 | 13837.9 | 1 | Mus musculus | ||
| 8 | J (L) | 23RSS non-integration strand (45-mer) | polymer | 45 | 13877.9 | 1 | Mus musculus | ||
| 9 | K, L (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, C: 261 - 1008 (UniProt: P15919)
B, D: 3 - 361 (UniProt: P21784)
| PDB | External Database | Details |
|---|---|---|
| Gly 259 | - | expression tag |
| Pro 260 | - | expression tag |
| Val 649 | Glu 649 | engineered mutation |
| Met 848 | Arg 848 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Met 1 | - | expression tag |
| Ala 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 323746.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 323877.2 |
