6XNB
The Crystal Structure of the S154Y Mutant Carbonyl Reductase from Leifsonia xyli Explains Enhanced Activity for 3,5-Bis(trifluoromethyl)acetophenone Reduction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Short chain alcohol dehydrogenase | polymer | 251 | 25064.1 | 1 | UniProt (T2FLN4) Pfam (PF13561) | Leifsonia xyli | |
| 2 | B, C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | E (A) | water | water | 18.0 | 328 | Chemie (HOH) |
Sequence modifications
A: 1 - 251 (UniProt: T2FLN4)
| PDB | External Database | Details |
|---|---|---|
| Tyr 154 | Ser 154 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25064.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 72.9 | |
| All* | Total formula weight | 25137.0 |
