6XLO
Crystal structure of bRaf in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase B-raf | polymer | 288 | 32832.6 | 2 | Pfam (PF07714) UniProt (by SIFTS) (P15056) | Homo sapiens (Human) | |
| 2 | C, E (A, B) | 3-(2-cyanopropan-2-yl)-N-[2-fluoro-4-methyl-5-(7-methyl-8-oxo-7,8-dihydropyrido[2,3-d]pyridazin-3-yl)phenyl]benzamide | non-polymer | 455.5 | 2 | Chemie (V5J) | |||
| 3 | D (A) | IODIDE ION | non-polymer | 126.9 | 1 | Chemie (IOD) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 65665.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1037.9 | |
| All* | Total formula weight | 66703.1 |
