6XKQ
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CV07-250
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Spike protein S1 | polymer | 231 | 26095.3 | 1 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) | |
| 2 | B (H) | CV07-250 Heavy Chain | polymer | 224 | 23966.7 | 1 | Homo sapiens | ||
| 3 | C (L) | CV07-250 Light Chain | polymer | 216 | 22862.2 | 1 | Homo sapiens | ||
| 4 | D, E (A, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | F, G, H (A, H, L) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 319 - 541 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Ser 542 | - | expression tag |
| Gly 543 | - | expression tag |
| His 544 | - | expression tag |
| His 545 | - | expression tag |
| His 546 | - | expression tag |
| His 547 | - | expression tag |
| His 548 | - | expression tag |
| His 549 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 72924.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 73366.6 |
