6XJ3
Crystal structure of Class D beta-lactamase from Klebsiella quasipneumoniae in complex with avibactam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase | polymer | 257 | 29676.5 | 4 | UniProt (Q4LAV3) Pfam (PF00905) | Klebsiella pneumoniae 700603 | |
| 2 | E, H, N, P (A, B, C, D) | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide | non-polymer | 267.3 | 4 | Chemie (NXL) | |||
| 3 | F, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | G, M (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | J, K, L (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | O (C) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 487 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 21 - 275 (UniProt: Q4LAV3)
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | - | expression tag |
| Asn 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 118706.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1713.8 | |
| All* | Total formula weight | 120419.9 |
