6XIC
PCSK9(deltaCRD) in complex with cyclic peptide 40
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proprotein convertase subtilisin/kexin type 9 | polymer | 121 | 13663.3 | 1 | UniProt (Q8NBP7) Pfam (PF05922) | Homo sapiens (human) | Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9 |
| 2 | B (B) | Proprotein convertase subtilisin/kexin type 9 | polymer | 308 | 32836.9 | 1 | UniProt (Q8NBP7) Pfam (PF00082) | Homo sapiens (human) | Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9 |
| 3 | C (I) | Peptide 40 | polymer | 9 | 1421.6 | 1 | synthetic construct | ||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E, F, G (A, B, I) | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
B: 153 - 452 (UniProt: Q8NBP7)
| PDB | External Database | Details |
|---|---|---|
| Asn 453 | - | expression tag |
| Ser 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 47921.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 92.1 | |
| All* | Total formula weight | 48014.0 |
