6XHO
Covalent complex of SARS-CoV main protease with ethyl (4R)-4-({N-[(4-methoxy-1H-indol-2-yl)carbonyl]-L-leucyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3C-like proteinase | polymer | 307 | 33933.7 | 2 | UniProt (P0C6U8) Pfam (PF05409) | Human SARS coronavirus (SARS-CoV) | |
| 2 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | D, E (A, B) | ethyl (2E,4S)-4-{[N-(4-methoxy-1H-indole-2-carbonyl)-L-leucyl]amino}-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate | non-polymer | 512.6 | 2 | Chemie (V34) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 420 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 306 (UniProt: P0C6U8)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67867.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1087.3 | |
| All* | Total formula weight | 68954.6 |
