6XG6

Full-length human mitochondrial Hsp90 (TRAP1) with ADP-BeF3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heat shock protein 75 kDa, mitochondrial, Fibronectin binding protein fusion	polymer	774	87094.6	2	UniProt (Q12931) UniProt (Q8G9G1) Pfam (PF00183) Pfam (PF02986) Pfam (PF17802)	Homo sapiens (Human)	HSP 75,TNFR-associated protein 1,Tumor necrosis factor type 1 receptor-associated protein,TRAP-1,Thioester-forming surface-anchored protein
2	C, G (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	D, H (A, B)	BERYLLIUM TRIFLUORIDE ION	non-polymer		66.0	2	Chemie (BEF)
4	E, I (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	F, J (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)

Sequence modifications

A, B: 60 - 704 (UniProt: Q12931)

PDB	External Database	Details
Gly 54	-	expression tag
Ile 55	-	expression tag
Asp 56	-	expression tag
Pro 57	-	expression tag
Phe 58	-	expression tag
Thr 59	-	expression tag
Gly 307	Arg 307	conflict
Gly 705	-	linker
Gly 706	-	linker
Ser 707	-	linker
Gly 708	-	linker
Ser 709	-	linker
Gly 710	-	linker
Ser 711	-	linker

A, B: 712 - 827 (UniProt: Q8G9G1)

PDB	External Database	Details
Ala 713	Arg 438	conflict
Met 714	Pro 439	conflict
Glu 748	Ile 473	conflict
Tyr 783	Met 508	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	174189.2
Non-Polymers*	Number of molecules	8
	Total formula weight	1113.2
All*	Total formula weight	175302.5

*Water molecules are not included.