6XEF
Crystal structure of the PTP1B YopH WPD loop Chimera 4 bound to vanadate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein phosphatase non-receptor type 1 | polymer | 321 | 37375.6 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (Human) | Protein-tyrosine phosphatase 1B,PTP-1B |
| 2 | B (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | VANADATE ION | non-polymer | 114.9 | 1 | Chemie (VO4) | |||
| 5 | F (A) | BENZAMIDINE | non-polymer | 120.2 | 1 | Chemie (BEN) | |||
| 6 | G (A) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence modifications
A: 1 - 321 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Asn 178 | Thr 178 | conflict |
| Gln 182 | Phe 182 | conflict |
| Thr 183 | Gly 183 | conflict |
| Ala 184 | Val 184 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37375.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 405.8 | |
| All* | Total formula weight | 37781.4 |
