6XDF
Crystal structure of IRE1a in complex with G-4100
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Serine/threonine-protein kinase/endoribonuclease IRE1 | polymer | 431 | 49303.3 | 2 | UniProt (O75460) Pfam (PF00069) Pfam (PF06479) In PDB | Homo sapiens (Human) | Endoplasmic reticulum-to-nucleus signaling 1,Inositol-requiring protein 1,hIRE1p,Ire1-alpha,IRE1a |
| 2 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 3 | A | 4-amino-N-(6-chloro-2-fluoro-3-{[(pyrrolidin-1-yl)sulfonyl]amino}phenyl)quinazoline-8-carboxamide | non-polymer | 464.9 | 1 | Chemie (N94) | |||
| 4 | water | water | 18.0 | 108 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 98606.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 510.9 | |
| All* | Total formula weight | 99117.4 |
