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6XD7

KPC-2 N170A mutant bound to hydrolyzed ampicillin at 1.65 A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carbapenem-hydrolyzing beta-lactamase KPCpolymer29331101.21UniProt (Q9F663)
Pfam (PF00144)
Pfam (PF13354)
Klebsiella pneumoniaeCarbapenem-hydrolyzing beta-lactamase KPC-1
2B
(A)
(2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acidnon-polymer367.41Chemie (ZZ7)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
waterwater18.0149Chemie (HOH)
Sequence modifications
A: 1 - 295 (UniProt: Q9F663)
PDBExternal DatabaseDetails
Ala 170Asn 169engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31101.2
Non-Polymers*Number of molecules2
Total formula weight459.5
All*Total formula weight31560.7
*Water molecules are not included.

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PDB entries from 2024-11-13

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