6XD7
KPC-2 N170A mutant bound to hydrolyzed ampicillin at 1.65 A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbapenem-hydrolyzing beta-lactamase KPC | polymer | 293 | 31101.2 | 1 | UniProt (Q9F663) Pfam (PF00144) Pfam (PF13354) In PDB | Klebsiella pneumoniae | Carbapenem-hydrolyzing beta-lactamase KPC-1 |
| 2 | A | (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid | non-polymer | 367.4 | 1 | Chemie (ZZ7) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 1 - 295 (UniProt: Q9F663)
| PDB | External Database | Details |
|---|---|---|
| Ala 170 | Asn 169 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31101.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 459.5 | |
| All* | Total formula weight | 31560.7 |
