6XCQ

Erythromycin esterase EreC, mutant H289N in its closed conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	EreC	polymer	438	48308.9	1	UniProt (C7C425)	Klebsiella pneumoniae	Erythromycin esterase
2	B (A)	S-1,2-PROPANEDIOL	non-polymer		76.1	1	Chemie (PGO)
3	C (A)	water	water		18.0	257	Chemie (HOH)

Sequence modifications

A: 1 - 418 (UniProt: C7C425)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Asn 289	His 289	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	48308.9
Non-Polymers*	Number of molecules	1
	Total formula weight	76.1
All*	Total formula weight	48385.0

*Water molecules are not included.