6XC9
Immune receptor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, F) | MHC class II HLA-DQ-alpha chain | polymer | 193 | 21929.3 | 2 | UniProt (Q30069) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B, F (C, H) | Hybrid Insulin Peptide, MHC class II HLA-DQ-beta chain fusion | polymer | 230 | 26071.0 | 2 | UniProt (A0A6B9KAL0) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (O19707) | Homo sapiens (Human) | |
| 3 | C, G (D, I) | T-CELL-RECEPTOR, A3.10-alpha chain | polymer | 208 | 23483.0 | 2 | Homo sapiens (Human) | ||
| 4 | D, H (E, J) | T-CELL-RECEPTOR, A3.10-beta chain | polymer | 245 | 27426.4 | 2 | Homo sapiens (Human) | ||
| 5 | I (B) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 6 | J (G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 7 | K, M, Q, R (A, C, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 8 | L, N, O, P, S... (C, D, F, H, I) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 9 | AA, BA, CA, V, W... (H, I, J, A, C...) | water | water | 18.0 | 391 | Chemie (HOH) |
Sequence modifications
A, F: -1 - 181 (UniProt: Q30069)
C, H: -2 - 14 (PDB: 6XC9)
C, H: 15 - 206 (UniProt: A0A6B9KAL0)
| PDB | External Database | Details |
|---|---|---|
| Cys 72 | Ile 75 | engineered mutation |
| Ser 182 | - | expression tag |
| Thr 183 | - | expression tag |
| Gly 184 | - | expression tag |
| Gly 185 | - | expression tag |
| Asp 186 | - | expression tag |
| Asp 187 | - | expression tag |
| Asp 188 | - | expression tag |
| Asp 189 | - | expression tag |
| Lys 190 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | linker |
| Gly 14 | - | linker |
| Ser 14 | - | linker |
| Ile 14 | - | linker |
| Glu 14 | - | linker |
| Gly 14 | - | linker |
| Arg 14 | - | linker |
| Gly 14 | - | linker |
| Gly 14 | - | linker |
| Ser 14 | - | linker |
| Gly 14 | - | linker |
| Ala 14 | - | linker |
| Ser 14 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Thr 207 | - | expression tag |
| Gly 208 | - | expression tag |
| Gly 209 | - | expression tag |
| Asp 210 | - | expression tag |
| Asp 211 | - | expression tag |
| Asp 212 | - | expression tag |
| Asp 213 | - | expression tag |
| Lys 214 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 197819.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1157.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1529.5 | |
| All* | Total formula weight | 200505.8 |
