6XC3

Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CC12.1 and CR3022

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	H	CR3022 heavy chain	polymer	222	23455.4	1		Homo sapiens
2	L	CR3022 light chain	polymer	221	24377.0	1		Homo sapiens
3	A	CC12.1 light chain	polymer	217	23641.4	1		Homo sapiens
4	B	CC12.1 heavy chain	polymer	220	23150.9	1		Homo sapiens
5	C	Spike protein S1	polymer	231	26095.3	1	UniProt (P0DTC2) Pfam (PF09408) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
6	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
7		water	water		18.0	170	Chemie (HOH)

Sequence modifications

C: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Ser 542	-	expression tag
Gly 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
His 546	-	expression tag
His 547	-	expression tag
His 548	-	expression tag
His 549	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	120720.0
Branched	Number of molecules	1
	Total formula weight	424.4
All*	Total formula weight	121144.4

*Water molecules are not included.