6XBY
Cryo-EM structure of V-ATPase from bovine brain, state 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | V-type proton ATPase catalytic subunit A | polymer | 617 | 68420.9 | 3 | UniProt (P31404) Pfam (PF02874) Pfam (PF16886) Pfam (PF00006) Pfam (PF22919) | Bos taurus (Bovine) | V-ATPase subunit A,V-ATPase 69 kDa subunit,Vacuolar proton pump subunit alpha |
| 2 | D, E, F (D, E, F) | V-type proton ATPase subunit B, brain isoform | polymer | 511 | 56637.6 | 3 | UniProt (P31408) Pfam (PF02874) Pfam (PF00006) Pfam (PF22919) | Bos taurus (Bovine) | V-ATPase subunit B 2,Endomembrane proton pump 58 kDa subunit,Vacuolar proton pump subunit B 2 |
| 3 | G (G) | V-type proton ATPase subunit C 1 | polymer | 382 | 44042.6 | 1 | UniProt (P21282) Pfam (PF03223) | Bos taurus (Bovine) | V-ATPase subunit C 1,Vacuolar proton pump subunit C 1 |
| 4 | H (H) | V-type proton ATPase subunit D | polymer | 247 | 28297.9 | 1 | UniProt (A0A3Q1M4W9) Pfam (PF01813) UniProt (by SIFTS) (P39942) | Bos taurus (Bovine) | |
| 5 | I, J, K (I, J, K) | V-type proton ATPase subunit E 1 | polymer | 226 | 26178.4 | 3 | UniProt (P11019) Pfam (PF01991) | Bos taurus (Bovine) | V-ATPase subunit E 1,V-ATPase 31 kDa subunit,P31,Vacuolar proton pump subunit E 1 |
| 6 | L (L) | V-type proton ATPase subunit F | polymer | 119 | 13417.3 | 1 | UniProt (Q28029) Pfam (PF01990) | Bos taurus (Bovine) | V-ATPase subunit F,V-ATPase 14 kDa subunit,Vacuolar proton pump subunit F |
| 7 | M, N, O (M, N, O) | V-type proton ATPase subunit G | polymer | 118 | 13588.3 | 3 | UniProt (Q0VCV6) Pfam (PF03179) | Bos taurus (Bovine) | |
| 8 | P (P) | V-type proton ATPase subunit H | polymer | 465 | 54155.9 | 1 | UniProt (F1MZL6) Pfam (PF03224) Pfam (PF11698) UniProt (by SIFTS) (O46563) | Bos taurus (Bovine) | |
| 9 | Q (a) | V-type proton ATPase subunit a | polymer | 838 | 96431.4 | 1 | UniProt (F1MJV0) Pfam (PF01496) UniProt (by SIFTS) (Q29466) | Bos taurus (Bovine) | |
| 10 | R (b) | V-type proton ATPase 21 kDa proteolipid subunit | polymer | 205 | 21530.4 | 1 | UniProt (Q2TA24) Pfam (PF00137) | Bos taurus (Bovine) | V-ATPase 21 kDa proteolipid subunit,Vacuolar proton pump 21 kDa proteolipid subunit |
| 11 | S (d) | V-type proton ATPase subunit d 1 | polymer | 351 | 40369.9 | 1 | UniProt (P61420) Pfam (PF01992) | Bos taurus (Bovine) | V-ATPase subunit d 1,32 kDa accessory protein,P39,V-ATPase 40 kDa accessory protein,V-ATPase AC39 subunit,Vacuolar proton pump subunit d 1 |
| 12 | AA, BA, T, U, V... (q, p, c, g, k...) | V-type proton ATPase 16 kDa proteolipid subunit | polymer | 155 | 15727.7 | 9 | UniProt (P23956) Pfam (PF00137) | Bos taurus (Bovine) | V-ATPase 16 kDa proteolipid subunit,Vacuolar proton pump 16 kDa proteolipid subunit |
| 13 | CA (s) | V-type proton ATPase subunit S1 | polymer | 468 | 51818.8 | 1 | UniProt (P40682) Pfam (PF05827) Pfam (PF20520) | Bos taurus (Bovine) | V-ATPase subunit S1,V-ATPase Ac45 subunit,V-ATPase S1 accessory protein,Vacuolar proton pump subunit S1 |
| 14 | DA (r) | Renin receptor | polymer | 351 | 39529.3 | 1 | UniProt (P81134) Pfam (PF07850) | Bos taurus (Bovine) | ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,Renin/prorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,V-ATPase M8.9 subunit |
| 15 | EA (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 16 | FA (D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 17 | GA, HA, IA, JA, QA... (b, l, o, s, r) | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 7 | Chemie (POV) | |||
| 18 | KA, LA, MA, NA, OA... (s) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 1025618.5 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 7099.3 | |
| All* | Total formula weight | 1032717.8 |
