6X8K
Caspase-3 in complex with elongated ketomethylene inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Caspase-3 | polymer | 175 | 19759.3 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
2 | C, D | Caspase-3 | polymer | 110 | 12981.8 | 2 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-3,Apopain,Cysteine protease CPP32,CPP-32,Protein Yama,SREBP cleavage activity 1,SCA-1 |
3 | E, F | ketomethylene inhibitor | polymer | 8 | 773.8 | 2 | synthetic construct | ||
4 | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
C, D: 176 - 277 (UniProt: P42574)
PDB | External Database | Details |
---|---|---|
Leu 278 | - | expression tag |
Glu 279 | - | expression tag |
His 280 | - | expression tag |
His 281 | - | expression tag |
His 282 | - | expression tag |
His 283 | - | expression tag |
His 284 | - | expression tag |
His 285 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 67029.8 | |
All* | Total formula weight | 67029.8 |