6X85
Crystal Structure of TNFalpha with indolinone compound 9
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Tumor necrosis factor | polymer | 158 | 17501.9 | 6 | UniProt (P01375) Pfam (PF00229) In PDB | Homo sapiens (Human) | Cachectin,TNF-alpha,Tumor necrosis factor ligand superfamily member 2,TNF-a |
2 | B | 1-{[2-(difluoromethoxy)phenyl]methyl}-2,2-dimethyl-1,2-dihydro-3H-indol-3-one | non-polymer | 317.3 | 1 | Chemie (UTV) |
Sequence modifications
A, B, C, D, E, F: 1 - 157 (UniProt: P01375)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 105011.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 317.3 | |
All* | Total formula weight | 105328.5 |