6X7C
BRD4 Bromodomain 1 in complex with multi-action inhibitor SRX3212
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 134 | 15854.3 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A | 7-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]-N-[(pyridin-3-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide | non-polymer | 505.5 | 1 | Chemie (KV9) | |||
| 3 | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 44 - 176 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15854.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 505.5 | |
| All* | Total formula weight | 16359.8 |
