6X7B
BRD4 Bromodomain 1 in complex with multi-action inhibitor SRX3212P
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bromodomain-containing protein 4 | polymer | 134 | 15854.3 | 2 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A, B | 7-[7-oxo-5-(piperazin-1-yl)-7H-thieno[3,2-b]pyran-3-yl]-N-[(pyridin-3-yl)methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide | non-polymer | 504.6 | 2 | Chemie (ZVP) | |||
| 3 | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A, B: 44 - 176 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31708.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1009.1 | |
| All* | Total formula weight | 32717.6 |
