6X6V
Crystal structure of inactive enzymatic binary toxin component from Clostridium difficile in complex with NADPH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | CdtA | polymer | 429 | 49536.8 | 4 | UniProt (F5B5W8) Pfam (PF03496) UniProt (by SIFTS) (Q9KH42) | Clostridioides difficile | |
| 2 | E, F, G, H (A, B, C, D) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 4 | Chemie (NDP) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 637 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 420 (UniProt: F5B5W8)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Val 1 | - | expression tag |
| Ala 2 | - | expression tag |
| Phe 345 | Ser 388 | conflict |
| Gln 385 | Glu 428 | conflict |
| Gln 387 | Glu 430 | conflict |
| Leu 421 | - | expression tag |
| Glu 422 | - | expression tag |
| His 423 | - | expression tag |
| His 424 | - | expression tag |
| His 425 | - | expression tag |
| His 426 | - | expression tag |
| His 427 | - | expression tag |
| His 428 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 198147.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2981.7 | |
| All* | Total formula weight | 201128.7 |
