6X4M
Human cyclophilin A bound to a series of acylcic and macrocyclic inhibitors: tert-butyl [(2S)-1-{[(3S,17S)-2,16-dioxo-10,15-dioxa-1,21-diazatricyclo[15.3.1.1~5,9~]docosa-5(22),6,8-trien-3-yl]amino}-3-methyl-1-oxobutan-2-yl]carbamate (compound 3)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peptidyl-prolyl cis-trans isomerase A | polymer | 167 | 18231.7 | 1 | UniProt (P62937) Pfam (PF00160) In PDB | Homo sapiens (Human) | PPIase A,Cyclophilin A,Cyclosporin A-binding protein,Rotamase A |
2 | A | tert-butyl [(2S)-1-{[(3S,17S)-2,16-dioxo-10,15-dioxa-1,21-diazatricyclo[15.3.1.1~5,9~]docosa-5(22),6,8-trien-3-yl]amino}-3-methyl-1-oxobutan-2-yl]carbamate | non-polymer | 546.7 | 1 | Chemie (UMM) | |||
3 | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A: 1 - 165 (UniProt: P62937)
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 18231.7 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 546.7 | |
All* | Total formula weight | 18778.4 |