6X1M
Lon protease proteolytic domain complexed with covalent boronic acid inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Lon protease homolog, mitochondrial | polymer | 218 | 23788.2 | 3 | UniProt (P36776) Pfam (PF05362) In PDB | Homo sapiens (Human) | LONHs,Lon protease-like protein,LONP,Mitochondrial ATP-dependent protease Lon,Serine protease 15 |
2 | A, B | [(1R)-4-phenyl-1-{[N-(pyrazine-2-carbonyl)-D-norvalyl]amino}butyl]boronic acid | non-polymer | 398.3 | 2 | Chemie (UKS) |
Sequence modifications
A, B, C: 754 - 959 (UniProt: P36776)
PDB | External Database | Details |
---|---|---|
Met 742 | - | initiating methionine |
Gly 743 | - | expression tag |
Ser 744 | - | expression tag |
Asp 745 | - | expression tag |
Lys 746 | - | expression tag |
Ile 747 | - | expression tag |
His 748 | - | expression tag |
His 749 | - | expression tag |
His 750 | - | expression tag |
His 751 | - | expression tag |
His 752 | - | expression tag |
His 753 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 71364.7 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 796.5 | |
All* | Total formula weight | 72161.2 |