6X0T
Structure of human plasma factor XIIa in complex with (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 8h)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Coagulation factor XII | polymer | 259 | 27936.6 | 3 | UniProt (P00748) Pfam (PF00089) In PDB | Homo sapiens (Human) | Hageman factor,HAF |
| 2 | A, B, C | (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide | non-polymer | 619.9 | 3 | Chemie (UJ7) | |||
| 3 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 83809.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1955.6 | |
| All* | Total formula weight | 85765.3 |
