6WYG
Crystal structure of Human H-chain Ferritin variant 157C Delta C-star Modified with a RAFT agent
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ferritin heavy chain | polymer | 182 | 21059.2 | 4 | UniProt (P02794) Pfam (PF00210) | Homo sapiens (Human) | Ferritin H subunit,Cell proliferation-inducing gene 15 protein |
| 2 | E, F, G, J, K... (A, B, C, D) | FE (III) ION | non-polymer | 55.8 | 9 | Chemie (FE) | |||
| 3 | H, L, M, Q, R... (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 4 | I, N, S, Y (A, B, C, D) | butyl 1-{[2-(2,5-dioxopyrrolidin-1-yl)ethyl]amino}-2-methyl-1-oxopropan-2-yl carbonotrithioate | non-polymer | 376.6 | 4 | Chemie (RFT) | |||
| 5 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 269 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 182 (UniProt: P02794)
| PDB | External Database | Details |
|---|---|---|
| Gln 86 | Lys 87 | engineered mutation |
| Glu 90 | Cys 91 | engineered mutation |
| Ala 102 | Cys 103 | engineered mutation |
| Ala 130 | Cys 131 | engineered mutation |
| Cys 157 | Lys 158 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 84236.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2329.5 | |
| All* | Total formula weight | 86566.3 |
