6WYD
CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-12 (AKA; 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyrid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, D, F, H) | Myeloperoxidase light chain | polymer | 105 | 11974.4 | 4 | UniProt (P05164) | Homo sapiens (Human) | MPO |
| 2 | B, D, F, H (B, E, G, I) | Myeloperoxidase heavy chain | polymer | 467 | 53305.3 | 4 | UniProt (P05164) Pfam (PF03098) | Homo sapiens (Human) | MPO |
| 3 | I, IA, JA, KA, KB... (A, E, F, I, B...) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 4 | AA, BA, CA, DA, DB... (E, I, B, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 19 | Chemie (NAG) | |||
| 5 | EA, HB, N, OA (E, I, B, G) | alpha-L-fucopyranose | non-polymer | 164.2 | 4 | Chemie (FUC) | |||
| 6 | FA, IB, O, PA (E, I, B, G) | HEME C | non-polymer | 618.5 | 4 | Chemie (HEC) | |||
| 7 | AB, Q, RA, X (I, B, G, E) | beta-D-mannopyranose | non-polymer | 180.2 | 4 | Chemie (BMA) | |||
| 8 | BB, CB, R, S, SA... (I, B, G, E) | alpha-D-mannopyranose | non-polymer | 180.2 | 8 | Chemie (MAN) | |||
| 9 | GA, T, UA, XA (E, B, G, H) | 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyridin-5-amine | non-polymer | 225.2 | 4 | Chemie (7GD) | |||
| 10 | HA, JB, U, VA (E, I, B, G) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 11 | LB, MB, NB, OB, PB... (A, B, D, E, F...) | water | water | 18.0 | 260 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 261118.7 | |
| Non-Polymers* | Number of molecules | 55 |
| Total formula weight | 10840.4 | |
| All* | Total formula weight | 271959.1 |
