6WYB
RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase | polymer | 774 | 90023.6 | 1 | UniProt (D0VWU9) Pfam (PF03104) Pfam (PF00136) | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | |
| 2 | B (B) | RNA strand | polymer | 16 | 5105.1 | 1 | Thermococcus kodakarensis KOD1 | ||
| 3 | C (C) | DNA strand | polymer | 13 | 3973.6 | 1 | Thermococcus kodakarensis KOD1 | ||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
| 6 | F, G, H, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 7 | J, K, L (A, B, C) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 1 - 774 (UniProt: D0VWU9)
| PDB | External Database | Details |
|---|---|---|
| Leu 38 | Phe 38 | conflict |
| Met 97 | Arg 97 | conflict |
| Ile 118 | Lys 118 | conflict |
| Leu 137 | Met 137 | conflict |
| His 147 | Glu 147 | conflict |
| Asp 210 | Asn 210 | conflict |
| His 381 | Arg 381 | conflict |
| His 384 | Tyr 384 | conflict |
| Ile 389 | Val 389 | conflict |
| Arg 466 | Lys 466 | conflict |
| Leu 493 | Tyr 493 | conflict |
| Ile 514 | Thr 514 | conflict |
| Leu 521 | Ile 521 | conflict |
| Lys 584 | Glu 584 | conflict |
| Leu 587 | Phe 587 | conflict |
| Lys 664 | Glu 664 | conflict |
| Val 711 | Gly 711 | conflict |
| Lys 735 | Asn 735 | conflict |
| Arg 768 | Trp 768 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99102.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 594.5 | |
| All* | Total formula weight | 99696.8 |
