6WYB
RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase | polymer | 774 | 90023.6 | 1 | UniProt (D0VWU9) Pfam (PF03104) Pfam (PF00136) In PDB | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | |
2 | B | RNA strand | polymer | 16 | 5105.1 | 1 | Thermococcus kodakarensis KOD1 | ||
3 | C | DNA strand | polymer | 13 | 3973.6 | 1 | Thermococcus kodakarensis KOD1 | ||
4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
5 | A | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
7 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 1 - 774 (UniProt: D0VWU9)
PDB | External Database | Details |
---|---|---|
Leu 38 | Phe 38 | conflict |
Met 97 | Arg 97 | conflict |
Ile 118 | Lys 118 | conflict |
Leu 137 | Met 137 | conflict |
His 147 | Glu 147 | conflict |
Asp 210 | Asn 210 | conflict |
His 381 | Arg 381 | conflict |
His 384 | Tyr 384 | conflict |
Ile 389 | Val 389 | conflict |
Arg 466 | Lys 466 | conflict |
Leu 493 | Tyr 493 | conflict |
Ile 514 | Thr 514 | conflict |
Leu 521 | Ile 521 | conflict |
Lys 584 | Glu 584 | conflict |
Leu 587 | Phe 587 | conflict |
Lys 664 | Glu 664 | conflict |
Val 711 | Gly 711 | conflict |
Lys 735 | Asn 735 | conflict |
Arg 768 | Trp 768 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 99102.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 594.5 | |
All* | Total formula weight | 99696.8 |