6WX9

SOX2 bound to Importin-alpha 5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Importin subunit alpha-5	polymer	467	51725.9	1	UniProt (P52294) Pfam (PF01749) Pfam (PF16186) Pfam (PF00514) In PDB	Homo sapiens (Human)	Karyopherin subunit alpha-1,Nucleoprotein interactor 1,NPI-1,RAG cohort protein 2,SRP1-beta
2	B	Transcription factor SOX-2	polymer	90	11045.0	1	UniProt (P48431) Pfam (PF00505) In PDB	Homo sapiens (Human)
3		water	water		18.0	36	Chemie (HOH)

Sequence modifications

A: 73 - 538 (UniProt: P52294)

PDB	External Database	Details
Ser 72	-	expression tag

B: 39 - 127 (UniProt: P48431)

PDB	External Database	Details
Ser 38	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62771.0
All*	Total formula weight	62771.0

*Water molecules are not included.