6WW9
Crystal structure of human REV7(R124A)-SHLD3(35-58) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Mitotic spindle assembly checkpoint protein MAD2B | polymer | 211 | 24237.2 | 2 | UniProt (Q9UI95) Pfam (PF02301) | Homo sapiens (Human) | Mitotic arrest deficient 2-like protein 2,MAD2-like protein 2,REV7 homolog,hREV7 |
| 2 | B, D (X, Y) | Shieldin complex subunit 3 | polymer | 35 | 4094.8 | 2 | UniProt (Q6ZNX1) | Homo sapiens (Human) | REV7-interacting novel NHEJ regulator 1,Shield complex subunit 3 |
Sequence modifications
A, B: 2 - 211 (UniProt: Q9UI95)
X, Y: 35 - 58 (UniProt: Q6ZNX1)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Ala 124 | Arg 124 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 34 | - | initiating methionine |
| Ala 59 | - | expression tag |
| Ser 60 | - | expression tag |
| Arg 61 | - | expression tag |
| Glu 62 | - | expression tag |
| Glu 63 | - | expression tag |
| Ile 64 | - | expression tag |
| Met 65 | - | expression tag |
| Ala 66 | - | expression tag |
| Thr 67 | - | expression tag |
| Leu 68 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56664.2 | |
| All* | Total formula weight | 56664.2 |






