6WW8
BRD4 Bromodomain 1 in complex with triple CDK4/6-PI3K-BET inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain-containing protein 4 | polymer | 138 | 16268.8 | 1 | UniProt (O60885) Pfam (PF00439) | Homo sapiens (Human) | Protein HUNK1 |
| 2 | B (A) | 7-cyclopentyl-N,N-dimethyl-2-({4-[5-(morpholin-4-yl)-7-oxo-7H-thieno[3,2-b]pyran-3-yl]phenyl}amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide | non-polymer | 584.7 | 1 | Chemie (YR0) | |||
| 3 | C (A) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 16268.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 584.7 | |
| All* | Total formula weight | 16853.4 |
