6WUR
Crystal structure of PRL-2 phosphatase C101D mutant in complex with the Bateman domain of CNNM3 magnesium transporter
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Protein tyrosine phosphatase type IVA 2 | polymer | 189 | 21868.2 | 1 | UniProt (Q12974) Pfam (PF00102) In PDB | Homo sapiens (Human) | HU-PP-1,OV-1,PTP(CAAXII),Protein-tyrosine phosphatase 4a2,Protein-tyrosine phosphatase of regenerating liver 2,PRL-2 |
2 | B | Metal transporter CNNM3 | polymer | 155 | 17634.0 | 1 | UniProt (Q8NE01) Pfam (PF00571) In PDB | Homo sapiens (Human) | Ancient conserved domain-containing protein 3,Cyclin-M3 |
3 | B | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
A: 1 - 167 (UniProt: Q12974)
B: 309 - 452 (UniProt: Q8NE01)
PDB | External Database | Details |
---|---|---|
Met -21 | - | initiating methionine |
Ser -20 | - | expression tag |
Tyr -19 | - | expression tag |
Tyr -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
Leu -11 | - | expression tag |
Glu -10 | - | expression tag |
Ser -9 | - | expression tag |
Thr -8 | - | expression tag |
Ser -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Lys -4 | - | expression tag |
Lys -3 | - | expression tag |
Ala -2 | - | expression tag |
Gly -1 | - | expression tag |
Phe 0 | - | expression tag |
Asp 101 | Cys 101 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly 298 | - | expression tag |
Pro 299 | - | expression tag |
Leu 300 | - | expression tag |
Asn 301 | - | expression tag |
Met 302 | - | expression tag |
Ile 303 | - | expression tag |
Gln 304 | - | expression tag |
Gly 305 | - | expression tag |
Val 306 | - | expression tag |
Leu 307 | - | expression tag |
Glu 308 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 39502.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 23.0 | |
All* | Total formula weight | 39525.2 |