6WSJ
Crystal Structure of Danio rerio histone deacetylase 6 catalytic domain 2 complexed with cyclopeptide des4.3.1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Hdac6 protein | polymer | 364 | 40285.5 | 1 | UniProt (A7YT55) Pfam (PF00850) UniProt (by SIFTS) (F8W4B7) In PDB | Danio rerio (Zebrafish) | Histone Deacetylase 6 |
| 2 | I | cyclopeptide des4.3.1 | polymer | 8 | 997.2 | 1 | BIRD (PRD_002383) | synthetic construct | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A: 440 - 798 (UniProt: A7YT55)
| PDB | External Database | Details |
|---|---|---|
| Ser 435 | - | expression tag |
| Asn 436 | - | expression tag |
| Ala 437 | - | expression tag |
| Gly 438 | - | expression tag |
| Gly 439 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41282.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 267.7 | |
| All* | Total formula weight | 41550.4 |
