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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6WRS

Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A50S ribosomal protein L19polymer11613392.81UniProt (A0A077UVB6)
Pfam (PF01245)
UniProt (by SIFTS) (Q2FZ42)
In PDB		Staphylococcus aureus
2B50S ribosomal protein L2polymer27730217.21UniProt (A0A077W1J0)
Pfam (PF00181)
Pfam (PF03947)
UniProt (by SIFTS) (P60430)
In PDB		Staphylococcus aureus
3C50S ribosomal protein L20polymer11813720.31UniProt (A0A077VMP6)
Pfam (PF00453)
UniProt (by SIFTS) (Q2FXQ1)
In PDB		Staphylococcus aureus
4D50S ribosomal protein L21polymer10511700.51UniProt (A0A0E0VQU6)
Pfam (PF00829)
UniProt (by SIFTS) (Q2FXS8)
In PDB		Staphylococcus aureus
5EuL22polymer11712871.91UniProt (A7X5F6)
Pfam (PF00237)
UniProt (by SIFTS) (Q2FW11)
In PDB		Staphylococcus aureus
6F50S ribosomal protein L23polymer9110627.31UniProt (W8TUB4)
Pfam (PF00276)
UniProt (by SIFTS) (Q2FW08)
In PDB		Staphylococcus aureus
7G50S ribosomal protein L24polymer10511591.51UniProt (W8TRD5)
Pfam (PF00467)
Pfam (PF17136)
UniProt (by SIFTS) (Q2FW17)
In PDB		Staphylococcus aureus
8HuL25polymer10712063.11UniProt (A0A2X2JWH5)
Pfam (PF01386)
UniProt (by SIFTS) (Q2G0S0)
In PDB		Staphylococcus aureus
9J50S ribosomal protein L28polymer626967.21UniProt (A0A077URJ8)
Pfam (PF00830)
UniProt (by SIFTS) (Q2FZ60)
In PDB		Staphylococcus aureus
10K50S ribosomal protein L29polymer728491.81UniProt (A0A2S6DIY7)
Pfam (PF00831)
UniProt (by SIFTS) (Q2FW14)
In PDB		Staphylococcus aureus
11L50S ribosomal protein L3polymer21723459.91UniProt (W8U3W0)
Pfam (PF00297)
UniProt (by SIFTS) (Q2FW06)
In PDB		Staphylococcus aureus
12M50S ribosomal protein L30polymer586434.51UniProt (W8UVN7)
Pfam (PF00327)
UniProt (by SIFTS) (P0A0G2)
In PDB		Staphylococcus aureus
13N50S ribosomal protein L32polymer576472.61UniProt (A0A077UWR7)
Pfam (PF01783)
UniProt (by SIFTS) (Q2FZF1)
In PDB		Staphylococcus aureus
14O50S ribosomal protein L33polymer495885.81UniProt (A0A077UXT4)
Pfam (PF00471)
UniProt (by SIFTS) (Q2FY22)
In PDB		Staphylococcus aureus
15P50S ribosomal protein L34polymer506064.41UniProt (T1YD75)
Pfam (PF00468)
UniProt (by SIFTS) (Q2FUQ0)
In PDB		Staphylococcus aureus
16Q50S ribosomal protein L35polymer657593.21UniProt (A0A077UL47)
Pfam (PF01632)
UniProt (by SIFTS) (Q2FXQ0)
In PDB		Staphylococcus aureus
17R50S ribosomal protein L36polymer374318.41UniProt (A0A077UGV8)
Pfam (PF00444)
UniProt (by SIFTS) (Q2FW29)
In PDB		Staphylococcus aureus
18S50S ribosomal protein L4polymer20722523.81UniProt (A0A166DK89)
Pfam (PF00573)
UniProt (by SIFTS) (Q2FW07)
In PDB		Staphylococcus aureus
19V50S ribosomal protein L13polymer14516359.41UniProt (W8TUE6)
Pfam (PF00572)
UniProt (by SIFTS) (Q2FW38)
In PDB		Staphylococcus aureus
20W50S ribosomal protein L14polymer12213157.31UniProt (A0A077UUA0)
Pfam (PF00238)
UniProt (by SIFTS) (Q2FW16)
In PDB		Staphylococcus aureus
21X50S ribosomal protein L15polymer14615628.91UniProt (A0A077UGA7)
Pfam (PF00828)
UniProt (by SIFTS) (P0A0F8)
In PDB		Staphylococcus aureus
22Y50S ribosomal protein L16polymer14416274.01UniProt (A0A077V4G0)
Pfam (PF00252)
UniProt (by SIFTS) (Q2FW13)
In PDB		Staphylococcus aureus
23Z50S ribosomal protein L17polymer12213771.81UniProt (A0A077UG91)
Pfam (PF01196)
UniProt (by SIFTS) (Q2FW33)
In PDB		Staphylococcus aureus
24a50S ribosomal protein L18polymer11913124.11UniProt (W8TRE0)
Pfam (PF00861)
UniProt (by SIFTS) (Q2FW22)
In PDB		Staphylococcus aureus
25123S rRNApolymer2923946680.61GenBank (1760383645)Staphylococcus aureus
2625S rRNApolymer11536958.01GenBank (1750990749)Staphylococcus aureus
27I50S ribosomal protein L27polymer859198.41UniProt (A0A077ULC5)
Pfam (PF01016)
UniProt (by SIFTS) (Q2FXT0)
In PDB		Staphylococcus aureus
281Tedizolidnon-polymer370.31Chemie (U7V)
Sequence modifications
E: 1 - 117 (UniProt: A7X5F6)
PDBExternal DatabaseDetails
Ala 110Gly 110variant
F: 1 - 91 (UniProt: W8TUB4)
PDBExternal DatabaseDetails
Asp 87Ile 87variant
G: 1 - 105 (UniProt: W8TRD5)
PDBExternal DatabaseDetails
Ser 54Gly 54variant
J: 1 - 61 (UniProt: A0A077URJ8)
PDBExternal DatabaseDetails
Ala 62-insertion
N: 1 - 57 (UniProt: A0A077UWR7)
PDBExternal DatabaseDetails
Ala 54Val 54variant
1: 1 - 2923 (GenBank: 1760383645)
PDBExternal DatabaseDetails
A 1866G 560294conflict
2: 1 - 115 (GenBank: 1750990749)
PDBExternal DatabaseDetails
C 80G 187450variant
C 109G 187479variant
A 111C 187481variant
G 112A 187482variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains27
Total formula weight1295548.7
Non-Polymers*Number of molecules1
Total formula weight370.3
All*Total formula weight1295919.0
*Water molecules are not included.

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PDB entries from 2024-07-10

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