6WRE

Crystal structure of mouse DXO in complex with 5'-OH RNA substrate mimic and calcium ion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Decapping and exoribonuclease protein	polymer	378	43132.5	1	UniProt (O70348) Pfam (PF08652) In PDB	Mus musculus (Mouse)	DXO,Dom-3 homolog Z
2	D	RNA (5'-R(*UP*(U37)P*(U37)P*UP)-3')	polymer	6	1824.2	1		Homo sapiens
3	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
4	A	3'-URIDINEMONOPHOSPHATE	non-polymer		324.2	1	Chemie (U3P)
5		water	water		18.0	128	Chemie (HOH)

Sequence modifications

A: 27 - 384 (UniProt: O70348)

PDB	External Database	Details
Met 7	-	initiating methionine
Gly 8	-	expression tag
Ser 9	-	expression tag
Ser 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Ser 17	-	expression tag
Ser 18	-	expression tag
Gly 19	-	expression tag
Leu 20	-	expression tag
Val 21	-	expression tag
Pro 22	-	expression tag
Arg 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
His 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44956.7
Non-Polymers*	Number of molecules	2
	Total formula weight	364.3
All*	Total formula weight	45321.0

*Water molecules are not included.