6WLZ

The V1 region of human V-ATPase in state 1 (focused refinement)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	V-type proton ATPase catalytic subunit A	polymer	617	68379.9	3	UniProt (P38606) Pfam (PF02874) Pfam (PF16886) Pfam (PF00006) In PDB	Homo sapiens (Human)	V-ATPase subunit A,V-ATPase 69 kDa subunit,Vacuolar ATPase isoform VA68,Vacuolar proton pump subunit alpha
2	D, E, F	V-type proton ATPase subunit B, brain isoform	polymer	511	56561.5	3	UniProt (P21281) Pfam (PF02874) Pfam (PF00006) In PDB	Homo sapiens (Human)	V-ATPase subunit B 2,Endomembrane proton pump 58 kDa subunit,HO57,Vacuolar proton pump subunit B 2
3	X, Y, Z	SidK	polymer	573	65505.3	3	UniProt (Q5ZWW6) In PDB	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
4	J, I, H	V-type proton ATPase subunit E 1	polymer	226	26183.3	3	UniProt (P36543) Pfam (PF01991) In PDB	Homo sapiens (Human)	V-ATPase subunit E 1,V-ATPase 31 kDa subunit,p31,Vacuolar proton pump subunit E 1
5	M, L, K	V-type proton ATPase subunit G 1	polymer	118	13781.5	3	UniProt (O75348) Pfam (PF03179) In PDB	Homo sapiens (Human)	V-ATPase subunit G 1,V-ATPase 13 kDa subunit 1,Vacuolar proton pump subunit G 1,Vacuolar proton pump subunit M16
6	G	V-type proton ATPase subunit D	polymer	247	28311.9	1	UniProt (Q9Y5K8) Pfam (PF01813) In PDB	Homo sapiens (Human)	V-ATPase subunit D,V-ATPase 28 kDa accessory protein,Vacuolar proton pump subunit D
7	N	V-type proton ATPase subunit F	polymer	119	13388.2	1	UniProt (Q16864) Pfam (PF01990) In PDB	Homo sapiens (Human)	V-ATPase subunit F,V-ATPase 14 kDa subunit,Vacuolar proton pump subunit F
8	C	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)

Contents of the asymmetric unit

Polymers	Number of chains	17
	Total formula weight	732934.8
Non-Polymers*	Number of molecules	1
	Total formula weight	427.2
All*	Total formula weight	733362.0

*Water molecules are not included.