6WLY

PAK4 kinase domain in complex with LIMK1 Thr508 substrate peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein kinase PAK 4	polymer	346	39123.1	1	UniProt (O96013) Pfam (PF00069)	Homo sapiens (Human)	p21-activated kinase 4,PAK-4
2	B (B)	LIM Kinase 1 peptide	polymer	10	1224.5	1	UniProt (P53667)	Homo sapiens	LIMK-1
3	C, D (A, B)	water	water		18.0	135	Chemie (HOH)

Sequence modifications

A: 274 - 591 (UniProt: O96013)

PDB	External Database	Details
Met 246	-	expression tag
Gly 247	-	expression tag
Ser 248	-	expression tag
Ser 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
Ser 256	-	expression tag
Ser 257	-	expression tag
Gly 258	-	expression tag
Leu 259	-	expression tag
Val 260	-	expression tag
Pro 261	-	expression tag
Arg 262	-	expression tag
Gly 263	-	expression tag
Ser 264	-	expression tag
His 265	-	expression tag
Met 266	-	expression tag
Glu 267	-	expression tag
Asn 268	-	expression tag
Leu 269	-	expression tag
Tyr 270	-	expression tag
Phe 271	-	expression tag
Gln 272	-	expression tag
Gly 273	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40347.6
All*	Total formula weight	40347.6

*Water molecules are not included.