6WLX

PAK4 kinase domain in complex with beta-catenin Ser675 substrate peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine/threonine-protein kinase PAK 4	polymer	346	39123.1	1	UniProt (O96013) Pfam (PF00069)	Homo sapiens (Human)	p21-activated kinase 4,PAK-4
2	B (B)	Catenin beta-1	polymer	7	862.0	1	UniProt (P35222)	Homo sapiens	Beta-catenin
3	C (A)	water	water		18.0	54	Chemie (HOH)

Sequence modifications

A: 274 - 591 (UniProt: O96013)

PDB	External Database	Details
Met 246	-	expression tag
Gly 247	-	expression tag
Ser 248	-	expression tag
Ser 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
Ser 256	-	expression tag
Ser 257	-	expression tag
Gly 258	-	expression tag
Leu 259	-	expression tag
Val 260	-	expression tag
Pro 261	-	expression tag
Arg 262	-	expression tag
Gly 263	-	expression tag
Ser 264	-	expression tag
His 265	-	expression tag
Met 266	-	expression tag
Glu 267	-	expression tag
Asn 268	-	expression tag
Leu 269	-	expression tag
Tyr 270	-	expression tag
Phe 271	-	expression tag
Gln 272	-	expression tag
Gly 273	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	39985.2
All*	Total formula weight	39985.2

*Water molecules are not included.