6WLW
The Vo region of human V-ATPase in state 1 (focused refinement)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (0) | V-type proton ATPase 21 kDa proteolipid subunit | polymer | 205 | 21418.2 | 1 | UniProt (Q99437) Pfam (PF00137) | Homo sapiens (Human) | V-ATPase 21 kDa proteolipid subunit,Vacuolar proton pump 21 kDa proteolipid subunit,hATPL |
| 2 | B, C, D, E, F... (1, 2, 3, 4, 5...) | V-type proton ATPase 16 kDa proteolipid subunit | polymer | 155 | 15743.7 | 9 | UniProt (P27449) Pfam (PF00137) | Homo sapiens (Human) | V-ATPase 16 kDa proteolipid subunit,Vacuolar proton pump 16 kDa proteolipid subunit |
| 3 | K (Q) | V-type proton ATPase subunit d 1 | polymer | 351 | 40369.9 | 1 | UniProt (P61421) Pfam (PF01992) | Homo sapiens (Human) | V-ATPase subunit d 1,32 kDa accessory protein,V-ATPase 40 kDa accessory protein,V-ATPase AC39 subunit,p39,Vacuolar proton pump subunit d 1 |
| 4 | L (R) | V-type proton ATPase 116 kDa subunit a isoform 1 | polymer | 837 | 96512.4 | 1 | UniProt (Q93050) Pfam (PF01496) | Homo sapiens (Human) | V-ATPase 116 kDa isoform a1,Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit,Vacuolar adenosine triphosphatase subunit Ac116,Vacuolar proton pump subunit 1,Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1 |
| 5 | M (S) | V-type proton ATPase subunit e 1 | polymer | 81 | 9380.3 | 1 | UniProt (O15342) Pfam (PF05493) | Homo sapiens (Human) | V-ATPase subunit e 1,V-ATPase 9.2 kDa membrane accessory protein,V-ATPase M9.2 subunit,Vacuolar proton pump subunit e 1 |
| 6 | N (T) | Ribonuclease kappa | polymer | 137 | 15435.2 | 1 | UniProt (Q6P5S7) | Homo sapiens (Human) | RNase kappa |
| 7 | O (U) | V-type proton ATPase subunit S1 | polymer | 470 | 52067.5 | 1 | UniProt (Q15904) Pfam (PF05827) Pfam (PF20520) | Homo sapiens (Human) | V-ATPase subunit S1,Protein XAP-3,V-ATPase Ac45 subunit,V-ATPase S1 accessory protein,Vacuolar proton pump subunit S1 |
| 8 | P (V) | Renin receptor | polymer | 350 | 39045.9 | 1 | UniProt (O75787) Pfam (PF07850) | Homo sapiens (Human) | ATPase H(+)-transporting lysosomal accessory protein 2,ATPase H(+)-transporting lysosomal-interacting protein 2,ER-localized type I transmembrane adapter,Embryonic liver differentiation factor 10,N14F,Renin/prorenin receptor,Vacuolar ATP synthase membrane sector-associated protein M8-9,V-ATPase M8.9 subunit |
| 9 | Q (W) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | branched | 998.9 | 1 | In PDB GlyTouCan (G48558GR) | |||
| 10 | R (A) | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose | branched | 836.7 | 1 | In PDB GlyTouCan (G50886AE) | |||
| 11 | S, U, V, W, X (s, u, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 12 | T (r) | alpha-D-glucopyranose-(1-2)-alpha-D-glucopyranose-(1-3)-alpha-D-glucopyranose-(1-3)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1883.7 | 1 | In PDB GlyTouCan (G71069MN) | |||
| 13 | AA, BA, EA, GA, RA... (0, 1, 3, R, U...) | tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium | non-polymer | 787.1 | 10 | Chemie (WSS) | |||
| 14 | CA, CB, DA, FA, JA... (0, V, 2, 5, 6...) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 13 | Chemie (PTY) | |||
| 15 | HA (3) | (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid | non-polymer | 497.4 | 1 | Chemie (WJS) | |||
| 16 | AB, BB, IA, OA (V, 5, R) | CHOLESTEROL | non-polymer | 386.7 | 4 | Chemie (CLR) | |||
| 17 | PA (R) | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE | non-polymer | 455.4 | 1 | Chemie (PSF) | |||
| 18 | SA (R) | methyl (3R,6Z,10E,14E)-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraen-1-yl dihydrogen diphosphate | non-polymer | 534.6 | 1 | Chemie (WJP) | |||
| 19 | YA (U) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 415922.4 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 5841.3 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 20669.0 | |
| All* | Total formula weight | 442432.6 |
