6WKU

Twelve Chloride Ions Drive Assembly of Human alpha345 Collagen IV NC1 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Collagen alpha-3(IV) chain,Collagen alpha-4(IV) chain,Collagen alpha-5(IV) chain	polymer	695	76707.0	1	UniProt (Q01955) UniProt (P53420) UniProt (P29400) Pfam (PF01413) In PDB	Homo sapiens (Human)	Goodpasture antigen
2	A	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
3	A	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
4	A	TRIETHYLENE GLYCOL	non-polymer		150.2	20	Chemie (PGE)
5	A	TETRAETHYLENE GLYCOL	non-polymer		194.2	10	Chemie (PG4)
6	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	24	Chemie (PEG)
7	A	1,2-ETHANEDIOL	non-polymer		62.1	30	Chemie (EDO)
8	A	PENTAETHYLENE GLYCOL	non-polymer		238.3	1	Chemie (1PE)
9	A	3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL	non-polymer		370.4	1	Chemie (PE8)
10		water	water		18.0	357	Chemie (HOH)

Sequence modifications

A: -1 - 226 (UniProt: Q01955)

PDB	External Database	Details
Ala -16	-	expression tag
Pro -15	-	expression tag
Leu -14	-	expression tag
Ala -13	-	expression tag
Asp -12	-	expression tag
Tyr -11	-	expression tag
Lys -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Lys -5	-	expression tag
Leu -4	-	expression tag
Ala -3	-	expression tag
Gly -2	-	expression tag
Gly 227	-	linker
Thr 228	-	linker

A: 229 - 451 (UniProt: P53420)

PDB	External Database	Details
Ala 452	-	linker
Pro 453	-	linker

A: 454 - 678 (UniProt: P29400)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	76707.0
Non-Polymers*	Number of molecules	93
	Total formula weight	10458.4
All*	Total formula weight	87165.5

*Water molecules are not included.