6WIV
Structure of human GABA(B) receptor in an inactive state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Gamma-aminobutyric acid type B receptor subunit 1 | polymer | 810 | 91585.9 | 1 | UniProt (Q9UBS5) Pfam (PF01094) Pfam (PF00003) | Homo sapiens (Human) | Gb1 |
| 2 | B (B) | Gamma-aminobutyric acid type B receptor subunit 2 | polymer | 827 | 93278.8 | 1 | UniProt (O75899) Pfam (PF01094) Pfam (PF00003) Pfam (PF18455) | Homo sapiens (Human) | Gb2,G-protein coupled receptor 51,HG20 |
| 3 | C, D, E, L (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 5 | G (A) | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 766.0 | 1 | Chemie (U3G) PubChem (52924645) PubChem (75957631) PubChem (134772896) PubChem (162809374) | |||
| 6 | H, I, J, K, N... (A, B) | CHOLESTEROL | non-polymer | 386.7 | 10 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (304) PubChem (176980071) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (18640088) PubChem (1715243) PubChem (1715244) PubChem (45044259) PubChem (23423981) PubChem (49853509) PubChem (50990013) PubChem (52934537) PubChem (56621683) PubChem (191463) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (368063) PubChem (369319) PubChem (44654663) PubChem (59450329) PubChem (59628412) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (46937002) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (638019) PubChem (59274407) PubChem (1549081) PubChem (1553803) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (89951918) PubChem (90224410) PubChem (5997) PubChem (5283629) PubChem (5284644) PubChem (1551269) PubChem (90070115) PubChem (91298236) PubChem (5315842) PubChem (117965027) PubChem (6432564) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (6419195) PubChem (10861996) PubChem (132837164) PubChem (101624109) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (124225449) PubChem (138967089) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (139566851) PubChem (124429284) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (15939944) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (171828367) PubChem (173516975) PubChem (130459183) PubChem (131992107) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 7 | M (B) | [(2R)-3-[(Z)-icos-11-enoyl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate | non-polymer | 814.2 | 1 | Chemie (U3D) PubChem (52923113) PubChem (134761268) |
Sequence modifications
A: 1 - 802 (UniProt: Q9UBS5)
B: 1 - 819 (UniProt: O75899)
| PDB | External Database | Details |
|---|---|---|
| Asp 803 | - | expression tag |
| Tyr 804 | - | expression tag |
| Lys 805 | - | expression tag |
| Asp 806 | - | expression tag |
| Asp 807 | - | expression tag |
| Asp 808 | - | expression tag |
| Asp 809 | - | expression tag |
| Lys 810 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asp 820 | - | expression tag |
| Tyr 821 | - | expression tag |
| Lys 822 | - | expression tag |
| Asp 823 | - | expression tag |
| Asp 824 | - | expression tag |
| Asp 825 | - | expression tag |
| Asp 826 | - | expression tag |
| Lys 827 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 184864.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 6371.7 | |
| All* | Total formula weight | 191236.3 |
