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6WI7

RING1B-BMI1 fusion in closed conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1 chimerapolymer21124322.71UniProt (X6RFN3)
UniProt (P35226)
Pfam (PF13923)
UniProt (by SIFTS) (Q99496)
Homo sapiens (Human)Polycomb group RING finger protein 4,RING finger protein 51
2B, C, D, E
(A)
ZINC IONnon-polymer65.44Chemie (ZN)
3F
(A)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
4G
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5H
(A)
waterwater18.0273Chemie (HOH)
Sequence modifications
A: 10 - 116 (UniProt: X6RFN3)
A: 1001 - 1104 (UniProt: P35226)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24322.7
Non-Polymers*Number of molecules6
Total formula weight592.0
All*Total formula weight24914.8
*Water molecules are not included.

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PDB entries from 2025-12-17

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