6WFG
Crystal structure of human Naa50 in complex with an inhibitor (compound 3) identified using DNA encoded library technology
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | N-alpha-acetyltransferase 50 | polymer | 171 | 19571.5 | 3 | UniProt (Q9GZZ1) Pfam (PF00583) In PDB | Homo sapiens (Human) | hNaa50p,N-acetyltransferase 13,N-acetyltransferase 5,hNAT5,N-acetyltransferase san homolog,hSAN,N-epsilon-acetyltransferase 50,NatE catalytic subunit, Naa50 |
| 2 | A, C, E | COENZYME A | non-polymer | 767.5 | 3 | Chemie (COA) | |||
| 3 | A, C, E | (2S)-N-[(2S)-3-[1-(3-tert-butyl-1-methyl-1H-pyrazole-5-carbonyl)piperidin-4-yl]-1-(methylamino)-1-oxopropan-2-yl]-6-oxopiperidine-2-carboxamide | non-polymer | 474.6 | 3 | Chemie (U3V) | |||
| 4 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 169 (UniProt: Q9GZZ1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 58714.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 3726.4 | |
| All* | Total formula weight | 62440.9 |
