6WF5
Crystal structure of human Naa50 in complex with a truncated cofactor derived inhibitor (compound 2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | N-alpha-acetyltransferase 50 | polymer | 171 | 19571.5 | 2 | UniProt (Q9GZZ1) Pfam (PF00583) | Homo sapiens (Human) | hNaa50p,N-acetyltransferase 13,N-acetyltransferase 5,hNAT5,N-acetyltransferase san homolog,hSAN,N-epsilon-acetyltransferase 50,NatE catalytic subunit, Naa50 |
| 2 | C, D (C, D) | ACE-MET-LEU-GLY-PRO-NH2 | polymer | 6 | 440.6 | 2 | synthetic construct | ||
| 3 | E, F (C, D) | (2R)-2-hydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide | non-polymer | 262.4 | 2 | Chemie (U44) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 169 (UniProt: Q9GZZ1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 40024.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 524.7 | |
| All* | Total formula weight | 40548.9 |
