6WEQ
DENV1 NS1 in complex with neutralizing 2B7 Fab fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Non-structural protein 1 | polymer | 376 | 42795.5 | 4 | UniProt (Q9J7C6) Pfam (PF00948) | Dengue virus 1 | |
| 2 | E, G, I, K (E, G, I, K) | 2B7 Fab fragment heavy chain | polymer | 268 | 28651.4 | 4 | Mus musculus (mouse) | ||
| 3 | F, H, J, L (F, H, J, L) | 2B7 Fab fragment light chain | polymer | 238 | 26204.0 | 4 | Mus musculus (mouse) | ||
| 4 | M, N, O, P, Q... (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 5 | S (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A, B, C, D: 0 - 352 (UniProt: Q9J7C6)
| PDB | External Database | Details |
|---|---|---|
| Ala -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Gly -14 | - | expression tag |
| Val -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Leu -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Asn -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 390603.7 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1865.7 | |
| All* | Total formula weight | 392469.4 |
