6WEQ
DENV1 NS1 in complex with neutralizing 2B7 Fab fragment
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Non-structural protein 1 | polymer | 376 | 42795.5 | 4 | UniProt (Q9J7C6) Pfam (PF00948) In PDB | Dengue virus 1 | |
2 | E, G, I, K | 2B7 Fab fragment heavy chain | polymer | 268 | 28651.4 | 4 | Mus musculus (mouse) | ||
3 | F, H, J, L | 2B7 Fab fragment light chain | polymer | 238 | 26204.0 | 4 | Mus musculus (mouse) | ||
4 | A, B, C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
5 | C | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A, B, C, D: 0 - 352 (UniProt: Q9J7C6)
PDB | External Database | Details |
---|---|---|
Ala -23 | - | expression tag |
His -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
Ser -16 | - | expression tag |
Ser -15 | - | expression tag |
Gly -14 | - | expression tag |
Val -13 | - | expression tag |
Asp -12 | - | expression tag |
Leu -11 | - | expression tag |
Gly -10 | - | expression tag |
Thr -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Ser -2 | - | expression tag |
Asn -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 390603.7 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1865.7 | |
All* | Total formula weight | 392469.4 |